Biocatalysis Publications

  • Native amine dehydrogenases can catalyze the direct reduction of carbonyl compounds to alcohols in the absence of ammonia
    16/06/2023

    Aurélie Fossey-Jouenne, Laurine Ducrot, P. J. Jongkind, Eddy Elisée, Anne Zaparucha, Gideon Grogan, Caroline E. Paul and Carine Vergne-Vaxelaire
    Front. Catal., 2023, Volume 3

  • Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering
    31/08/2022

    Laurine Ducrot, Megan Bennett, Dr. Gwenaëlle André-Leroux, Dr. Eddy Elisée, Sacha Marynberg, Aurélie Fossey-Jouenne, Prof. Anne Zaparucha, Prof. Gideon Grogan, Dr. Carine Vergne-Vaxelaire
    ChemCatChem, 2022, 14(22)

  • Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2
    29/03/2022

    Bennett M, Ducrot L, Vergne-Vaxelaire C, Grogan G
    Chembiochem, 2022, Volume23, Issue10

  • Synthesis of Chiral Amines via a Bi-Enzymatic Cascade Using an Ene-Reductase and Amine Dehydrogenase
    21/01/2022

    Jongkind E., Fossey-Jouenne A., Mayol O., Zaparucha A., Vergne-Vaxelaire C., Paul E.
    ChemCatChem, 2022, Volume 14, Issue 2

  • Biocatalytic Reductive Amination by Native Amine Dehydrogenases to Access Short Chiral Alkyl Amines and Amino Alcohols
    26/11/2021

    Ducrot L., Bennett M., Caparco A., Champion J., Bommarius A., Zaparucha A., Grogan G., Vergne-Vaxelaire C.
    Front. Catal., 2021, 1

  • Nitrilase immobilization and transposition from a micro-scale batch to a continuous process increase the nicotinic acid productivity
    16/07/2021

    Teepakorn C, Zajkoska P, Cwicklinski G, De Berardinis V, Zaparucha A, Nonglaton G and Anxionnaz-Minvielle Z
    Biotechnology Journal, 2021, 16 (10)

  • Purification and Characterization of Nitphym, a Robust Thermostable Nitrilase From Paraburkholderia phymatum
    01/07/2021

    Thomas Bessonnet, Aline Mariage, Jean-Louis Petit, Virginie Pellouin, Adrien Debard, Anne Zaparucha, Carine Vergne-Vaxelaire, Véronique de Berardinis
    Front Bioeng Biotechnol, 2021, Volume 9

  • Complete Genome Sequences of Two Pseudomonas Species Isolated from Marine Environments of the Pacific Ocean
    22/04/2021

    Shi-Zhen Wang, Corinne Cruaud, Jean-Marc Aury, David Vallenet, Julie Poulain, Benoit Vacherie, Anne Zaparucha, Carine Vergne-Vaxelaire
    Microbiol Resour Announc, 2021, Volume 10 Issue 16

  • NAD(P)H-Dependent Enzymes for Reductive Amination: Active Site Description and Carbonyl-Containing Compound Spectrum
    19/01/2021

    Laurine Ducrot, Megan Bennett, Gideon Grogan, Carine Vergne-Vaxelaire
    Adv. Synth. Catal., 363 (2), 328-351, 2021

  • Metagenomic Mining for Amine Dehydrogenase Discovery
    15/06/2020

    Caparco A., A.Pelletier E., Petit JL., Jouenne A., Bommarius B., de Berardinis V., Zaparucha A., Champion J., Bommarius A., Vergne-Vaxelaire C.
    Adv. Synth. Catal., 2020, 362(12), 2427-2436

  • ATP regeneration system in chemoenzymatic amide bond formation with thermophilic CoA ligase
    20/02/2020

    Lelièvre C. M., Balandras M., Petit J.-L., Vergne-Vaxelaire C., Zaparucha A.
    ChemCatChem 2020, 12, 1184-1192

  • XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii
    31/10/2019

    Jérémy Domergue, Diane Erdmann, Aurélie Fossey‑Jouenne, Jean‑Louis Petit, Adrien Debard, Véronique de Berardinis, Carine Vergne‑Vaxelaire and Anne Zaparucha
    AMB Expr, 2019, 9, 175

  • A family of native amine dehydrogenases for the asymmetric reductive amination of ketones
    18/03/2019

    Mayol O., Bastard K., Beloti L., Frese A., Turkenburg J., Petit JL., Mariage A., Debard A., Pellouin V., Perret A., de Berardinis V., Zaparucha A., Grogan G., Vergne-Vaxelaire C.
    Nat. Catal., 2019, 2, 324-333

  • Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family
    08/11/2018

    Bastard K., Isabet T., Stura E. A., Legrand P., Zaparucha A.
    Sci. Rep. 2018, 8:16587

  • Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
    16/02/2018

    Fossey-Jouenne A., Vergne-Vaxelaire C., Zaparucha A.
    J. Vis. Exp. 2018, 132

  • Biocatalytic Approaches towards the Synthesis of Chiral Amino Alcohols from Lysine: Cascade Reactions Combining AlphaKetoAcid Oxygenase Hydroxylation with Pyridoxal Phosphate Dependent Decarboxylation
    02/05/2017

    Baud D., Peruch O., Saaidi P.-L., Fossey A., Mariage A., Petit J.-L., Salanoubat M., Vergne-Vaxelaire C., de Berardinis V., Zaparucha A.
    Adv. Syn. Catal. 2017, 359, 1563-1569

  • Asymmetric reductive amination by a wild-type amine dehydrogenase from the thermophilic bacteria Petrotoga mobilis
    01/08/2016

    Mayol O., David S., Darii E., Debard A., Mariage A., Pellouin V., Petit JL., Salanoubat M., de Berardinis V., Zaparucha A., Vergne-Vaxelaire C.
    Catal. Sc. Technol. 2016, 6, 7421-7428

  • Synthesis of Mono- and Dihydroxylated Amino Acids with New α-Ketoglutarate-Dependent Dioxygenases: Biocatalytic Oxidation of CH Bonds
    11/09/2014

    Baud D., Saaidi P.-L., Monfleur A., Harari M., Cuccaro J., Fossey A., Besnard M., Debard A., Mariage A., Pellouin V., Petit J.-L., Salanoubat M., Weissenbach J., de Berardinis V., Zaparucha A.
    Chem. Cat. Chem. 2014, 6, 3012-3017

  • Large α-aminonitrilase activity screening of nitrilase superfamily members: Access to conversion and enantiospecificity by LC–MS
    01/06/2014

    Bordier F., Stam M., Darii E., Tricot S., Fossey A., Rohault J., Debard A., Mariage A., Pellouin V., Petit J.-L., Perret A., Vallenet D., Salanoubat M., Weissenbach J., Vergne-Vaxelaire C., Zaparucha A.
    J. Mol. Cat. B :enzymatic 2014, 107, 79-88

  • Nitrilase Activity Screening on Structurally Diverse Substrates: Providing Biocatalytic Tools for Organic Synthesis
    04/06/2013

    Vergne-Vaxelaire C, Bordier F., Fossey A., Besnard-Gonnet M., Debard A., Mariage A., Pellouin V., Perret A., Petit J.-L., Stam M., Salanoubat M., Weissenbach J., de Berardinis V., Zaparucha A.
    Adv. Syn. Catal. 2013, 355, 1763-1779