Synthetic Metabolism : Science Labs

Synthetic Metabolism

Our synthetic metabolism projects focus on designing, implementing, and improving artificial routes for one-carbon assimilation and carbon-efficient biosynthesis. By coupling rational design with experimental evolution and continuous culture strategies, we build robust microbial systems adapted to non-conventional feedstocks.

This integrated approach combines pathway engineering, enzyme selection, and physiological optimization to unlock new production capabilities in microbial hosts.

Projects

Silent Glycolysis Formate dependent growth Oxidoreductases specificity and adaptive evolution Continuous culture adaptation Sensor strain for testing Reductive route of one-carbon assimilation In-vivo assimilation of one-carbon Synthetic alternative to canonical one-carbon

Past Projects

Project A Project B Project C Project D

Publications

Engineering robust enzymes for selective biocatalysis in complex media Integrated biodegradation pathways for sustainable pollutant removal Synthetic metabolism design principles for next-generation microbial factories Data-driven optimization of biosynthetic fluxes in industrial hosts

Learn more